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Incorporating SDOH into real-world data analyses to improve patient outcomes

Clinical care is estimated to influence only 10-20% of the modifiable factors contributing to health outcomes, with the remaining 80- 90% shaped by health-related behaviors, socioeconomic factors, and the physical environment. While commonly overlooked, the incorporation of social drivers of health (SDOH) data into realworld data analyses can unlock much more precise and nuanced insights related to unmet needs, healthcare disparities, and the performance of therapies in various subpopulations.

For life sciences companies, access to SDOH data is essential for understanding how therapies are performing in diverse, real-world populations. Factors such as age, sex, geographic ancestry, and environmental conditions impact treatment responses and drug effectiveness. Real-world evidence linked to SDOH data can address gaps in knowledge about product safety and effectiveness in particular populations, thus driving product innovation, patient education, and access initiatives.

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